Author

J. Manji

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Akarca· 1 shared A. Dey· 1 shared A. K. Fielding· 1 shared C. A. Mendoza· 1 shared C. D. Steele· 1 shared C. Mancusi· 1 shared D. Auty· 1 shared E. Cutler· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Akarca

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Author profile →

2 papers

Recent·Most cited

Mitochondrial dsRNA from B-ALL cells stimulates mesenchymal stromal cells to become cancer associated fibroblasts

R. J. Burt, A. Dey, A. Akarca, H. Allen, R. Amerikanou, S. Atkinson, D. Auty, J. Chatzigerou, E. Cutler, J. A. Guerra-Assuncao, K. Kirschner, R. Kumari, J. Manji, T. Marafioti, A. K. Fielding

This study shows that mitochondrial dsRNA from B-ALL cells triggers MSC to become CAFs, linking genetic subtypes to survival outcomes.

bioRxiv · Sep 26, 2023Cancer Biology

Therapeutic vulnerability to PARP1/2 inhibition in RB1-mutant osteosarcoma

G. Zoumpoulidou, C. A. Mendoza, C. Mancusi, R. M. Ahmed, M. Denman, C. D. Steele, J. Manji, N. Pillay, S. J. Strauss, S. Mittnacht

This study shows RB1-mutant osteosarcoma is hypersensitive to PARP1/2 inhibitors, with sensitivity linked to replication checkpoint activation rather than homologous repair defects.

bioRxiv · Dec 28, 2020 · PreprintCancer Biology