ImmunologyThe EMBO ReportsPeer-reviewed
Aire-dependent transcripts escape H3K36me3 and Raver2 induced alternative splicing to sustain central immune tolerance
F. Padonou, V. Gonzalez, N. Jmari…·M. Giraud
The paper identifies that Aire-sensitive genes in mTECs escape Raver2 and H3K36me3 regulation, leading to reduced alternative splicing and impacting central immune tolerance.
DOI 10.15252/embr.202153576