J. McCarty

Biochemical characterization of Bacillus anthracis sortase B: Use in sortase mediated ligation and substrate recognition dependent on residues beyond the canonical pentapeptide binding motif for sortase enzymes

This study characterizes Bacillus anthracis SrtB, showing that residues outside the canonical pentapeptide motif are critical for activity and that engineered variants can improve ligation efficiency.

Killer Immunoglobulin-like Receptor-Ligand Interactions Predict Clinical Outcomes Following Unrelated Donor Transplants

The paper develops a mathematical model to quantify KIR-KIRL interactions and shows that these interactions predict clinical outcomes in HLA-matched unrelated donor transplants.

Narrow equilibrium window for complex coacervation of tau and RNA under cellular conditions

This study identifies the narrow conditions under which tau and RNA form reversible coacervates and fibrils, revealing entropy-driven LLPS under physiological conditions.

Th17/regulatory T cells balance is predictive of Coccidioides infection outcome in pediatric patients

The paper identifies Th17 and Treg cell balance as predictors of Coccidioides infection outcome in pediatric patients, finding higher Treg frequencies in persistent infections.