Transition from Transient DNA Rereplication to Inherited Gene Amplification Following Prolonged Environmental Stress
G. M. Wright, J. Menzel, P. D. Tatman, J. C. Black
The paper shows that prolonged metal exposure causes DNA rereplication at the MT locus, leading to transient gene amplifications that can become inherited through homologous recombination.
bioRxiv · May 8, 2023 · PreprintCell Biology