Author

J. Kraxner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

S. Koester· 4 shared C. Lorenz· 2 shared H. Witt· 2 shared J. Forsting· 2 shared A. Janshoff· 1 shared A. V. Schepers· 1 shared B. Fabry· 1 shared B. Schwappach· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersBiophysics

S. Koester

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Contractility of cardiac and skeletal muscle tissue increases with environmental stiffness

D. Kah, J. Lell, T. Wach, M. Spoerrer, C. A. Dessalles, J. Kraxner, S. Wiedenmann, R. C. Gerum, S. Vergarajauregui, T. U. Esser, D. Boehringer, F. B. Engel, I. Thievessen, B. Fabry

This study shows that contractile force in cardiac and skeletal muscle tissues increases with environmental stiffness following a power-law relationship.

bioRxiv · Feb 23, 2024 · PreprintBiophysics

Vimentin filaments integrate low complexity domains in a highly complex helical structure

M. Eibauer, M. S. Weber, R. Kronenberg-Tenga, C. T. Beales, R. Boujemaa-Paterski, Y. Turgay, S. Sivagurunathan, J. Kraxner, S. Koester, R. D. Goldman, O. Medalia

This study determines the 3D structure of vimentin intermediate filaments, revealing how disordered domains contribute to their mechanical properties.

bioRxiv · May 22, 2023Biochemistry

Post-Translational Modifications Soften Vimentin Intermediate Filaments

J. Kraxner, C. Lorenz, J. Menzel, I. Parfentev, I. Silbern, M. Denz, H. Urlaub, B. Schwappach, S. Koester

This study investigates how post-translational modifications, specifically phosphorylation and 14-3-3 binding, affect the mechanical properties of vimentin intermediate filaments.

bioRxiv · Jun 5, 2020Biophysics

Vimentin intermediate filaments undergo irreversible conformational changes during cyclic loading

J. Forsting, J. Kraxner, H. Witt, A. Janshoff, S. Koester

This study shows vimentin intermediate filaments undergo irreversible conformational changes under cyclic loading, introducing a third state to explain their mechanical behavior.

bioRxiv · Sep 25, 2019Biophysics

Lateral Subunit Coupling Determines Intermediate Filament Mechanics

C. Lorenz, J. Forsting, A. V. Schepers, J. Kraxner, S. Bauch, H. Witt, S. Klumpp, S. Koester

This study compares the mechanical properties of keratin and vimentin filaments, showing vimentin's mechanics depend on ionic strength and involve strong lateral subunit coupling.

bioRxiv · Jun 19, 2019Biophysics