Cell BiologybioRxiv
Feedback control of Wnt signaling based on histidine cluster co-aggregation between Naked/NKD and Axin
M. Gammons, M. Renko, J. E. Flack…·M. Bienz
This study identifies a feedback mechanism in Wnt signaling where Naked/NKD's histidine cluster aggregation destabilizes Axin and Dishevelled, regulating prolonged Wnt responses.
DOI 10.7554/elife.59879