An inducible CRISPR-ON system for controllable gene activation in human pluripotent stem cells
J. Guo, D. Ma, R. Huang, J. Ming, M. Ye, K. Kee, Z. Xie, J. Na
This paper develops an inducible CRISPR-ON system to controllably activate genes in human pluripotent stem cells, demonstrating its ability to regulate NANOG expression and enhance cell survival and integration with mouse blastocysts.
bioRxiv · Feb 5, 2017Cell Biology