Author

J. Muffat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

F. Sun· 2 shared A. Chai· 1 shared A. Dadvar· 1 shared A. Gandhi· 1 shared A. P. McGuigan· 1 shared A. Rosenstein· 1 shared B. Murareanu· 1 shared C. A. Simmons· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

F. Sun

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

FAST-STEM: A human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices

A. Rosenstein, R. Sambathkumar, B. Murareanu, N. Dhaliwal, F. Sun, X. Zhao, A. Dadvar, R. Al-attar, A. Chai, N. Gulati, T. Yin, M. Nguyen, D. Serra, T. Devina, A. Gandhi, , M. J. Garton

FAST-STEM accelerates human pluripotent stem cell engineering by enabling rapid transgene integration and differentiation into multiple cell types.

bioRxiv · May 23, 2024 · PreprintBioengineering

EHMT2/G9a-Inhibition Reprograms Cancer-Associated Fibroblasts (CAFs) to a More Differentiated, Less Proliferative and Invasive State

N. C. Wu, R. Quevedo, M. Nurse, K. Hezaveh, H. Liu, F. Sun, J. Muffat, Y. Sun, C. A. Simmons, T. L. McGaha, P. Prinos, C. H. Arrowsmith, L. Ailles, E. D'Arcangelo, A. P. McGuigan

This study identifies EHMT2 as a key regulator of CAF hyperproliferation and pro-invasive behavior, showing its inhibition reprograms CAFs to a less aggressive state.

bioRxiv · Jul 17, 2023 · PreprintCancer Biology