Author

J. Ostrop

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Diez-Sanchez· 2 shared H. T. Lindholm· 2 shared M. J. Oudhoff· 2 shared N. Parmar· 2 shared C. Arrowsmith· 1 shared F. Gerbe· 1 shared J. P. von Kries· 1 shared K. B. Jensen· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

A. Diez-Sanchez

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2 papers

Recent·Most cited

Postnatal intestinal epithelial maturation by LSD1 controls the small intestinal immune cell composition independently from the microbiota

A. Diez-Sanchez, H. T. Lindholm, P. M. Vornewald, J. Ostrop, N. Parmar, T. N. Shaw, M. Martin-Alonso, M. J. Oudhoff

This study shows that LSD1 in intestinal epithelial cells controls immune cell composition postnatally, independent of microbiota.

bioRxiv · Sep 8, 2023Immunology

A semi-automated intestinal organoid screening method demonstrates epigenetic control of epithelial differentiation

J. Ostrop, R. Zwiggelaar, M. T. Pedersen, F. Gerbe, K. Bösl, H. T. Lindholm, A. Diez-Sanchez, N. Parmar, S. Radetzki, J. P. von Kries, P. Jay, K. B. Jensen, C. Arrowsmith, M. J. Oudhoff

This study develops a semi-automated intestinal organoid screening method to identify epigenetic regulators of epithelial differentiation, finding that inhibiting type I PRMTs enhances differentiation and blocks adenoma growth.

bioRxiv · Jul 23, 2020Cell Biology