BioengineeringbioRxiv
Heat-triggered remote control of CRISPR-dCas9 for tunable transcriptional modulation
L. Gamboa, E. V. Phung, H. Li…·G. Kwong
This paper introduces a method to remotely control CRISPR-dCas9 activity using heat, allowing dynamic transcriptional modulation in mammalian cells.
DOI 10.1021/acschembio.9b01005