PhysiologybioRxiv
Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis
B. S. Sahu, M. Razzoli, S. McGonigle…·A. Bartolomucci
This study creates a mouse model with a selective knockout of the TLQP-21 neuropeptide, revealing its role in temperature-dependent resistance to diet-induced obesity and brown adipose tissue activation.
DOI 10.1016/j.molmet.2023.101781