Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin
A. Belyy, F. Lindemann, D. Roderer, J. Funk, B. Bardiaux, J. Protze, P. Bieling, H. Oschkinat, S. Raunser
This study reveals how TccC3 toxin modifies F-actin by ADP-ribosylating threonine-148, disrupting actin dynamics and causing cell death.
bioRxiv · May 6, 2022Biochemistry