Author

J. Q. Tran

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

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D. J. Irvine· 1 shared E. Demissie· 1 shared F. Alsufyani· 1 shared G. J. Yuen· 1 shared J. J. Moon· 1 shared S. Kumari· 1 shared S. Pillai· 1 shared V. Mahajan· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperImmunology

D. J. Irvine

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1 paper

Recent·Most cited

ImmunologybioRxivMar 20, 2019

DOCK2 sets the threshold for entry into the virtual memory CD8+ T cell compartment by negatively regulating tonic TCR triggering

E. Demissie, V. Mahajan, F. Alsufyani…·S. Pillai

This study shows that DOCK2 deficiency leads to increased virtual memory CD8+ T cells by enhancing TCR sensitivity to weak agonists and reducing tonic TCR triggering.

DOI 10.4049/jimmunol.1900440

mousebulk RNA-seq

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