Author

J. R. Baker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

L. E. Donnelly· 2 shared P. J. Barnes· 2 shared P. S. Fenwick· 2 shared A. A. Kennedy· 1 shared A. Attari· 1 shared A. W. Tai· 1 shared C. K. Coss· 1 shared H. B. Owles· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

L. E. Donnelly

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Extracellular vesicles propagate aging in COPD airway epithelial cells by transfer of microRNA-34a

J. V. Devulder, J. R. Baker, P. S. Fenwick, L. Odqvist, L. E. Donnelly, P. J. Barnes

This study shows that extracellular vesicles from COPD airway cells transfer miR-34a to healthy cells, inducing senescence by reducing SIRT1 and increasing p21CIP1.

bioRxiv · Dec 18, 2023 · PreprintCell Biology

Imbalance between IL-36 receptor agonist and antagonist drives neutrophilic inflammation in COPD

J. R. Baker, P. S. Fenwick, C. K. Coss, H. B. Owles, S. L. Elkin, M. Thomas, J. Fine, K. C. El-Kasmi, P. J. Barnes, L. E. Donnelly

The paper identifies an imbalance between IL-36 receptor agonist and antagonist in COPD patients, showing it drives neutrophilic inflammation and suggests a therapeutic antibody targeting IL-36R as a potential treatment.

bioRxiv · Oct 6, 2021Cell Biology

A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine

S. Jangra, J. J. Landers, R. Rathnasinghe, J. J. O'Konek, K. W. Janczak, M. Cascalho, A. A. Kennedy, A. W. Tai, J. R. Baker, M. Schotsaert, P. T. Wong

This study develops a combination adjuvant that enhances antiviral immune responses to a SARS-CoV-2 protein vaccine, showing improved TH1 responses and neutralizing antibodies against variants in mice.

bioRxiv · Feb 18, 2021Immunology

Comparison of Anorectal Function Measured using Wearable Digital Manometry and a High Resolution Manometry System.

A. Attari, W. D. Chey, J. R. Baker, J. A. Ashton-Miller

This study compares a low-cost digital manometry system with high-resolution manometry for assessing anorectal function, finding similar results at lower cost and comparable patient comfort.

bioRxiv · Jan 24, 2020Bioengineering