Author

J. Fine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

G. Chopra· 2 shared A. Casanal· 1 shared A. Greenstein· 1 shared A. Leader· 1 shared A. Rahman· 1 shared C. Chang· 1 shared C. K. Arya· 1 shared C. K. Coss· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

G. Chopra

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Imbalance between IL-36 receptor agonist and antagonist drives neutrophilic inflammation in COPD

J. R. Baker, P. S. Fenwick, C. K. Coss, H. B. Owles, S. L. Elkin, M. Thomas, J. Fine, K. C. El-Kasmi, P. J. Barnes, L. E. Donnelly

The paper identifies an imbalance between IL-36 receptor agonist and antagonist in COPD patients, showing it drives neutrophilic inflammation and suggests a therapeutic antibody targeting IL-36R as a potential treatment.

bioRxiv · Oct 6, 2021Cell Biology

Integration of Biodynamic Imaging and RNA-seq classifies chemotherapy response in canine diffuse large B-cell lymphoma

J. Fine, S. Utturkar, D. Dhawan, G. Chopra, S. Utturkar, J. Turek, D. Nolte, M. O. Childress, N. A. Lanman

This study combines BioDynamic Imaging and RNA-seq data to develop a model predicting chemotherapy response in canine DLBCL by integrating gene expression and phenotypic biomarkers.

bioRxiv · Sep 11, 2020 · PreprintCancer Biology

Breaking a Strong Amide Bond: Structure and Properties of Dimethylformamidase.

C. K. Arya, S. Yadav, J. Fine, A. Casanal, G. Chopra, G. Ramanathan, K. R. Vinothkumar, R. Subramanian

This paper describes the structure and properties of Dimethylformamidase (DMFase) from Paracoccus, revealing new protein folds and a unique mononuclear iron active site that enables its function in harsh conditions.

bioRxiv · Dec 17, 2019Biochemistry

Single-cell analysis of Crohn’s disease lesions identifies a pathogenic cellular module associated with resistance to anti-TNF therapy

J. C. Martin, G. Boschetti, C. Chang, R. Ungaro, M. Giri, L.-S. Chuang, S. Nayar, A. Greenstein, M. Dubinsky, L. Walker, A. Leader, J. Fine, C. Whitehurst, L. Mbow, S. Kugathasan, , E. Kenigsberg

bioRxiv · Dec 20, 2018Immunology