Author

J. R. Mckinney

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Biophysics· 1

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Approach:experimental assay· 1

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E. F. McDonald· 1 shared J. A. Selvasingh· 1 shared J. Meiler· 1 shared K. V. Ledwitch· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperBiophysics

E. F. McDonald

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1 paper

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BiophysicsbioRxivPreprintMay 8, 2023

Dark nanodiscs as a model membrane for evaluating membrane protein thermostability by differential scanning fluorimetry

J. A. Selvasingh, E. F. McDonald, J. R. Mckinney…·J. Meiler

This paper introduces a method using dark nanodiscs and nanoDSF to measure membrane protein thermostability, showing a biphasic unfolding pattern for DsbB with two distinct melting temperatures.

DOI 10.1101/2023.05.08.539917

experimental assay

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