BiochemistrybioRxiv
IMPDH1 retinal variants control filament architecture to tune allosteric regulation
A. L. BURRELL, C. Nie, M. Said…·J. M. Kollman
The paper shows IMPDH1 retinal variants form different filaments that affect GTP regulation, with disease mutations disrupting or not affecting this regulation.
DOI 10.1038/s41594-021-00706-2