Author

J. R. Sims

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

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C. F. R. Ascencao· 1 shared D. Dibitetto· 1 shared K. Feng· 1 shared M. B. Smolka· 1 shared R. Freire· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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1 shared paperCancer Biology

C. F. R. Ascencao

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJan 13, 2020

ATR Inhibitors as Potent Modulators of DNA End Resection Capacity

D. Dibitetto, J. R. Sims, C. F. R. Ascencao…·M. B. Smolka

This study shows that long-term ATR inhibition reduces DNA end resection and DNA repair efficiency in cancer cells, offering a strategy to enhance PARP inhibitor sensitivity.

DOI 10.1101/2020.01.13.905059

humanDNA methylation

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