Intrinsically disordered interaction network in an RNA chaperone revealed by native mass spectrometry
S. H. Sarni, J. Roca, C. Du, M. Jia, H. Li, A. Damjanovic, E. Małecka, V. Wysocki, S. A. Woodson
This study uses native mass spectrometry and molecular dynamics to show how intrinsically disordered CTDs in Hfq form a network that integrates RNA contacts and stabilizes the hexamer.
bioRxiv · May 23, 2022Biophysics