Author

A. Moe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

J. L. Rubinstein· 3 shared P. Brzezinski· 3 shared A. Rayasam· 2 shared A. Szabo· 2 shared J. Di Trani· 2 shared W. Drobyski· 2 shared A. Zamora· 1 shared B. Moore· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

J. L. Rubinstein

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

MICROGLIAL CELL EXPRESSION OF THE TYPE 2 CANNABINOID RECEPTOR REGULATES IMMUNE-MEDIATED NEUROINFLAMMATION

A. Moe, A. Rayasam, G. Sauber, R. Shah, C. Y. Yuan, A. Szabo, B. Moore, M. Colonna, W. Cui, J. Romero, A. Zamora, C. Hillard, W. Drobyski

This study shows that CB2R on microglia drives neuroinflammation in GVHD by promoting T cell activation and neuronal death, and that targeting CB2R reduces inflammation without worsening systemic GVHD.

bioRxiv · Aug 10, 2023 · PreprintImmunology

A TYPE 2 INNATE LYMPHOID CELL-INTERLEUKIN 9 CIRCUIT INDUCES PANETH CELL METAPLASIA AND SMALL INTESTINAL REMODELING

C.-Y. Yuan, A. Rayasam, A. Moe, W. Xu, A. Szabo, M. Hayward, C. Wells, N. Salzman, W. Drobyski

This study identifies an ILC2/IL-9 immune circuit triggered by extra-intestinal disease that induces Paneth cell metaplasia and small intestinal remodeling in a murine model of CML.

bioRxiv · Nov 2, 2022Immunology

Structural basis of mammalian Complex IV inhibition by steroids

J. Di Trani, A. Moe, D. Riepl, P. Saura, V. R. I. Kaila, P. Brzezinski, J. L. Rubinstein

This study identifies a steroid-binding site on Complex IV and shows how steroid binding inhibits proton uptake through the K-pathway.

bioRxiv · Apr 13, 2022Biophysics

The respiratory supercomplex from C. glutamicum

A. Moe, T. Kovalova, S. Krol, D. J. Yanofsky, M. Bott, D. Sjöstrand, J. L. Rubinstein, M. Högbom, P. Brzezinski

This paper determines the structure of the CIII2CIV2 supercomplex from C. glutamicum using cryo-EM, revealing its architecture and proton transport pathway.

bioRxiv · Jun 16, 2021Biochemistry

Cryo-EM structure and kinetics reveal electron transfer by 2D diffusion of cytochrome c in the yeast III-IV respiratory supercomplex

A. Moe, J. Di Trani, J. L. Rubinstein, P. Brzezinski

This paper uses cryo-EM and kinetic studies to show that cytochrome c transfers electrons via 2D diffusion along the surface of yeast III2IV1/2 supercomplexes, enhancing electron transfer efficiency.

bioRxiv · Nov 27, 2020Biochemistry