BiochemistryNature Chemical BiologyPeer-reviewed
A small molecule VHL molecular glue degrader for cysteine dioxygenase 1
A. Tutter, D. Buckley, A. A. Golosov…·G. A. Michaud
The paper identifies a small molecule that acts as a molecular glue degrader for CDO1 by recruiting it into the VHL E3 ligase complex, leading to its degradation.
DOI 10.1038/s41589-025-01936-x