Author

A. Tutter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 3 Approach:deep learning· 2 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

F. Berst· 2 shared F. J. Zecri· 2 shared J. W. Mason· 2 shared K. Briner· 2 shared S. Bonazzi· 2 shared S. L. Schreiber· 2 shared W. Shu· 2 shared X. Ma· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

F. Berst

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A small molecule VHL molecular glue degrader for cysteine dioxygenase 1

A. Tutter, D. Buckley, A. A. Golosov, X. Ma, W. Shu, D. J. Mckay, V. Darsigny, D. Dovala, R. Beckwith, J. Solomon, P. Rao, L. Xu, A. Fazal, A. Lingel, C. Wartchow, , G. A. Michaud

The paper identifies a small molecule that acts as a molecular glue degrader for CDO1 by recruiting it into the VHL E3 ligase complex, leading to its degradation.

Nature Chemical Biology · Jun 24, 2025Peer-reviewedBiochemistry

Rational screening for cooperativity in small-molecule inducers of protein-protein associations

S. Liu, B. Tong, J. W. Mason, J. M. Ostrem, A. Tutter, B. K. Hua, S. A. Tang, S. Bonazzi, K. Briner, F. Berst, F. J. Zecri, S. L. Schreiber

The paper introduces a binding-based screen to identify cooperative small-molecule inducers of protein-protein interactions, identifying a compound with high cooperativity comparable to classical molecular glues.

bioRxiv · May 22, 2023Biophysics

DNA-encoded library (DEL)-enabled discovery of proximity-inducing small molecules

J. W. Mason, L. Hudson, M. V. Westphal, A. Tutter, G. Michaud, W. Shu, X. Ma, C. W. Coley, P. A. Clemons, S. Bonazzi, F. Berst, F. J. Zecri, K. Briner, S. L. Schreiber

This paper uses DNA-encoded libraries to discover small molecules that induce protein-protein associations between BRD4 and VHL-elongin C-elongin B.

bioRxiv · Oct 13, 2022Pharmacology & Toxicology