Author

J. S. Marchant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:electrophysiology· 1

Frequent Co-Authors

C. Rohr· 1 shared D. Maillard· 1 shared E. G. Chulkov· 1 shared F. Rippmann· 1 shared J. D. Chan· 1 shared L. Friedrich· 1 shared N. A. Yahya· 1 shared P. I. Dosa· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

C. Rohr

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivMar 9, 2021

Mechanism of praziquantel action at a parasitic flatworm ion channel

S.-K. Park, L. Friedrich, N. A. Yahya…·J. S. Marchant

This study identifies the mechanism by which praziquantel activates a specific ion channel in parasitic flatworms, explaining its efficacy against some species but not others.

DOI 10.1126/scitranslmed.abj5832

electrophysiologyexperimental assay

𝕏 PostBluesky

Pharmacology & ToxicologyJournal of Biological ChemistryPeer-reviewedDec 1, 2019

Praziquantel activates a schistosome transient receptor potential channel

S. K. Park, P. McCusker, P. I. Dosa…·J. S. Marchant

This study identifies a transient receptor potential channel as the target of praziquantel in schistosomes and other PZQ-sensitive parasites.

DOI 10.1074/jbc.ac119.011093

experimental assayhost-pathogen & immune response

𝕏 PostBluesky