Cancer BiologybioRxiv
Transglutaminase-2 facilitates extracellular vesicle-mediated establishment of the metastatic niche
A. Shinde, J. S. Paez, S. M. Libring…·M. Wendt
This study identifies TGM2 as a key factor in metastatic niche formation via extracellular vesicles in breast cancer, showing its role in enhancing metastasis through fibronectin crosslinking.
DOI 10.1038/s41389-020-0204-5