BiophysicsbioRxiv
Novel heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase
G. Gamiz-Arco, L. Gutierrez-Rus, V. Risso…·J. Sanchez-Ruiz
This study identifies a heme-binding site in an ancestral glycosidase, showing how heme binding rigidifies the TIM-barrel and enhances catalysis.
DOI 10.1038/s41467-020-20630-1