Author

J. Sanchis Martinez

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Evolutionary Biology· 1

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Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:simulation· 1 Approach:statistical model· 1

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A. Li· 1 shared C. G. Acevedo-Rocha· 1 shared L. D'Amore· 1 shared M. Ferla· 1 shared M. Garcia Borras· 1 shared M. T. Reetz· 1 shared P. Lubrano· 1 shared S. Hoebenreich· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperEvolutionary Biology

A. Li

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1 paper

Recent·Most cited

Evolutionary BiologybioRxivApr 14, 2020

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics

C. G. Acevedo-Rocha, A. Li, L. D'Amore…·M. T. Reetz

The paper quantifies cooperative mutational effects on multiple catalytic traits of a cytochrome P450 enzyme using computational methods and simulations, showing their modulation by long-range conformational dynamics.

DOI 10.1038/s41467-021-21833-w

protein structurestatistical model

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