J. Schaefer

Human endometrial KISS1R inhibits stromal cell decidualization in a manner associated with a reduction in ESR1 levels

This study shows KISS1R inhibits human endometrial stromal cell decidualization by reducing ESR1 levels, which affects embryo invasion and pregnancy success.

Sex Differences in Brain Tumor Glutamine Metabolism Reveal Sex-Specific Vulnerabilities to Treatment

The paper identifies sex differences in glutamine metabolism in glioblastomas, showing male tumors have higher glutamine uptake and are more sensitive to GLS1 inhibition than female tumors.

Assessing aneuploidy with repetitive element sequencing.

The paper describes a PCR-based assay for detecting aneuploidy in low DNA samples, showing 49% prevalence in non-metastatic cancers and 80% sensitivity when combined with other biomarkers.

ESCRT machinery mediates selective microautophagy of endoplasmic reticulum

This study identifies the ESCRT machinery and Nem1-Spo7 phosphatase complex as key components mediating micro-ER-phagy in yeast, distinguishing it from macro-ER-phagy.

Membrane capacitance recordings resolve dynamics and complexity of receptor-mediated endocytosis in Wnt signalling

The paper uses membrane capacitance recordings to study endocytosis dynamics in Wnt signaling, revealing distinct endocytic pathways for Wnt3a and Wnt5a in HEK293 cells.