tRNASer overexpression induces adaptive mutations in NSCLC tumors
M. Ferreira, M. Pinheiro, A. Reis, A. Andre, S. Rocha, M. A. S. Santos, M. Santos, C. Oliveira
This study shows that overexpressing tRNASer in NSCLC tumors increases mutation burden and generates variants that promote proliferation and therapy resistance.
bioRxiv · May 6, 2023 · PreprintCancer Biology