Author

J. Sotiris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

B. F. Malone· 1 shared B. T. Chait· 1 shared E. A. Campbell· 1 shared E. T. Eng· 1 shared E. Y. D. Chua· 1 shared H. Ng· 1 shared J. Chen· 1 shared J. H. Mendez· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

B. F. Malone

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1 paper

Recent·Most cited

Structural basis for substrate selection by the SARS-CoV-2 replicase

B. F. Malone, J. K. Perry, P. D. B. Olinares, J. Chen, T. K. Appleby, J. Y. Feng, J. P. Bilello, H. Ng, J. Sotiris, M. Ebrahim, E. Y. D. Chua, J. H. Mendez, E. T. Eng, R. Landick, B. T. Chait, , S. A. Darst

This study uses cryo-EM to reveal how the SARS-CoV-2 RTC discriminates between natural NTPs and the antiviral remdesivir triphosphate, providing insights for antiviral design.

bioRxiv · May 20, 2022Biophysics