In vivo reprogramming of murine host immune response genes following Leishmania major infection.
G. Venugopal, J. T. Bird, C. L. Washam…·T. Weinkopff
This study uses bulk and single-cell RNA sequencing to analyze gene expression changes in mice infected with Leishmania major, identifying upregulated immune pathways and downregulated ribosomal pathways, as well as a novel role for EIF2 signaling.