Author

J. Thomas Brenna

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Hui Gyu ParkiD· 2 shared Alon KeinaniD· 1 shared Bethany P. CummingsiD· 1 shared Blaine Harlan· 1 shared James Zou· 1 shared Ji Yao Zhang· 1 shared Kaixiong YeiD· 1 shared Kalpana S. Joshi· 1 shared

Activity by Year

2016-2021 · peak 1/yr

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10 top collaborators · 31 mutual co-author links

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2 shared papersGenomics

Hui Gyu ParkORCID

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2 papers

Recent·Most cited

GenomicsPLoS ONEPeer-reviewedDec 31, 2021

Single-cell Chromatin Accessibility and Lipid Profiling Reveals a Metabolic Shift in Adipocytes Induced by Bariatric Surgery

Blaine Harlan, Hui Gyu Park, Roman Spektor…·Paul D. Soloway

This study uses single-cell ATAC sequencing and lipid profiling to show that bariatric surgery alters chromatin accessibility and fatty acid profiles in adipose tissue, suggesting a metabolic shift mediated by Scd1.

2 citations

mousescATAC-seq

𝕏 PostBluesky

Evolutionary BiologybioRxivMar 6, 2016

Positive selection on a regulatory insertion-deletion polymorphism in FADS2 influences apparent endogenous synthesis of arachidonic acid

Kumar S.D. Kothapalli, Kaixiong Ye, Maithili S. Gadgil…·J. Thomas Brenna

The paper identifies a regulatory insertion-deletion polymorphism in FADS2 associated with increased arachidonic acid synthesis in individuals with a plant-based diet.

DOI 10.1093/molbev/msw049

humanstatistical model

𝕏 PostBluesky