Author

J. van Nes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:chicken / avian· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

F. Speleman· 2 shared J. Koster· 2 shared R. Versteeg· 2 shared S. Loontiens· 2 shared S. Mohlin· 2 shared A. Chan· 1 shared A. Lakeman· 1 shared A. Louwagie· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

F. Speleman

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Author profile →

3 papers

Recent·Most cited

MOXD1 is a gate-keeper of organ homeostasis and functions as a tumor-suppressor in neuroblastoma

E. Fredlund, S. Andersson, E. Hilgert, G. Alvarez-Hernan, E. Monferrer, S. Karakaya, T. Gregor, S. Loontiens, J. W. Bek, E. Lecomte, E. Magnusson, E. Miltenyte, M. Cabirol, M. Kyknas, N. Engstrom, , S. Mohlin

The paper identifies MOXD1 as a tumor-suppressor gene in neuroblastoma by analyzing bulk and single-cell RNA sequencing data and validating its role in organ homeostasis across multiple species.

bioRxiv · Jan 17, 2023 · PreprintCancer Biology

An immature subset of neuroblastoma cells synthesizes retinoic acid and depends on this metabolite

T. van Groningen, C. U. Niklasson, A. Chan, N. Akogul, E. M. Westerhout, K. von Stedingk, M. Hamdi, L. J. Valentijn, S. Mohlin, P. Stroeken, N. E. Hasselt, F. Haneveld, A. Lakeman, D. A. Zwijnenburg, P. van Sluis, , J. van Nes

The paper identifies an immature neuroblastoma subset that synthesizes retinoic acid and is resistant to it, potentially contributing to therapy-resistant relapses.

bioRxiv · May 18, 2021 · PreprintCancer Biology

SOX11 is a lineage-dependency factor and master epigenetic regulator in neuroblastoma

B. Decaesteker, A. Louwagie, S. Loontiens, F. De Vloed, J. Roels, S. Vanhauwaert, S. De Brouwer, E. Sanders, G. Denecker, E. D'haene, S. Van Haver, W. Van Loocke, J. Van Dorpe, D. Creytens, N. Van Roy, , F. Speleman

This study identifies SOX11 as a critical transcription factor and epigenetic regulator in adrenergic neuroblastoma, showing its role in chromatin accessibility and cell identity.

bioRxiv · Aug 21, 2020 · PreprintCancer Biology