Author

J. Verhejein

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Pharmacology & Toxicology· 1

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

E. Morava· 1 shared E. O. Perlstein· 1 shared F. S. Sam· 1 shared G. Preston· 1 shared H. Tsang· 1 shared J. Lao· 1 shared K. Murthy· 1 shared N. DiPrimio· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

E. Morava

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivSep 26, 2019

Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG

S. Iyer, F. S. Sam, N. DiPrimio…·E. O. Perlstein

This paper identifies epalrestat, an existing drug, as a PMM2 enzyme activator for PMM2-CDG, showing it improves enzyme activity in patient fibroblasts.

DOI 10.1242/dmm.040584

humanbulk RNA-seq

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