Author

J. W. Bruggeman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

G. Hamer· 2 shared A. M. M. van Pelt· 1 shared J. J. B. Koster· 1 shared J. Koster· 1 shared N. Irie· 1 shared P. Lodder· 1 shared S. Repping· 1 shared

Activity by Year

2017-2020 · peak 1/yr

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7 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

G. Hamer

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2 papers

Recent·Most cited

Cancer BiologybioRxivSep 8, 2020

Tumors widely express hundreds of embryonic germline genes

J. W. Bruggeman, N. Irie, P. Lodder…·G. Hamer

The paper identifies 672 germ cell cancer genes, expanding the known pool by 51%, and suggests they may offer better cancer treatment targets with fewer side effects.

DOI 10.3390/cancers12123812

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivSep 28, 2017

Massive expression of germ cell specific genes is a hallmark of cancer and a potential target for novel treatment development

J. W. Bruggeman, J. J. B. Koster, S. Repping, G. Hamer

The paper identifies hundreds of true germ cell specific genes expressed in tumors, which could be targeted for cancer therapy with minimal side effects.

DOI 10.1038/s41388-018-0357-2

humanbulk RNA-seq

𝕏 PostBluesky