Synaptotagmin-9 and Tomosyn-1 molecular complex regulates Stx1A SNAREs to inhibit insulin secretion from pancreatic beta-cells
M. M. Rahman, A. Pathak, K. L. Schueler, H. A. Alsharif, A. N. Michl, J. Alexander, J.-a. Kim, E. R. Chapman, S. Bhatnagar
This study shows that synaptotagmin-9 inhibits insulin secretion by forming a complex with Tomosyn-1 and Stx1A, reducing SNARE complex formation in pancreatic beta-cells.
bioRxiv · Oct 20, 2022 · PreprintCell Biology