SPIN1 promotes tumorigenesis by blocking the uL18-MDM2-p53 pathway
Z. Fang, J.-M. Liao, B. Cao, J. Deng, K. D. Plummer, P. Liao, T. Liu, S. X. Zeng, J. Xiong, H. Lu
This study identifies SPIN1 as a regulator of the uL18-MDM2-p53 pathway, showing that SPIN1 promotes tumorigenesis by inhibiting p53 activation.
bioRxiv · Aug 18, 2017Cancer Biology