J.-P. Parvy

Infection triggers tumor regression through activation of innate immunity in Drosophila

The study shows bacterial infections reduce tumor size in Drosophila by enhancing innate immune pathways like Imd and Toll.

The antimicrobial peptide Defensin cooperates with Tumour Necrosis Factor to drive tumour cell death in Drosophila

This study shows Defensin, an antimicrobial peptide, works with Tumour Necrosis Factor to kill tumour cells in Drosophila, demonstrating an in vivo anti-cancer role for an endogenous AMP.