Cancer BiologybioRxivPreprint
Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance
F. Li, Y. Wang, I. Hwang…·H. Zheng
The paper identifies KDM2A as a selective vulnerability in ALT-dependent cancers by showing its role in telomere cluster dissolution through SENP6-mediated SUMO deconjugation.
DOI 10.1101/2023.02.10.528023