Author
University of California, Irvine
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Devon F. Pendlebury, Khloe Truong, Marie C. Heath…·Leslie Michels Thompson
The paper investigates TDP-43 SUMOylation and its role in DNA damage repair under oxidative stress.
Thai B. Nguyen, Ricardo Miramontes, Carlos Chillón-Marinas…·Leslie Michels Thompson
This study identifies TDP-43 dysfunction and reduced m6A modification as mechanisms causing aberrant splicing in Huntington's disease using mouse and human brain data.
Ryan G. Lim, Osama Al‐Dalahmah, Jie Wu…·Leslie Michels Thompson
This study uses snRNAseq to analyze HD mouse models and human brain tissue, identifying impaired oligodendrocyte maturation and a potential role for thiamine metabolism in disease pathology.
Sandra M. Holley, Jack C. Reidling, Carlos Cepeda…·Leslie Michels Thompson
This study shows that human neural stem cells transplanted into Huntington's disease mouse models improve behavior, reduce mutant Huntingtin, and integrate functionally into the host brain.