NeurosciencebioRxivPreprint
Activation of KCC2 during development alleviates cognitive, behavioral, and neural excitability in adult CDKL5-deficient mice
Muhammad Nauman Arshad, Christopher E. Bope, Jacob S. Dengler…·Paul A Davies
This study shows that activating KCC2 during development reduces seizures, cognitive, and behavioral issues in adult CDKL5-deficient mice, but adult treatment is less effective.
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