Author

Jake B. Lewis

Newcastle University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1 Assay:proteomics· 1

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Elise McDonald· 1 shared Elizabeth A. VealiD· 1 shared Eloise Butler· 1 shared Emilia Dwyer· 1 shared Emma L Button· 1 shared Fiona Pearson· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperImmunology

Elise McDonald

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintMar 6, 2025

The 1-Cys peroxiredoxin, PRDX-6, suppresses a pro-survival response, including the Flavin monoxygenase, FMO-2, that protects against fungal and bacterial infection

Emma L Button, Jake B. Lewis, Emilia Dwyer…·Elizabeth A. Veal

This paper shows that loss of PRDX-6 in C. elegans increases stress resistance, innate immunity, and longevity by upregulating FMO-2, which protects against fungal and bacterial infections.

DOI 10.1101/2025.03.06.640586

C. elegansproteomics

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