Evolutionary BiologyPLOS GeneticsPeer-reviewed
Host-pathogen coevolution and the emergence of broadly neutralizing antibodies in chronic infections
Armita Nourmohammad, Jakub Otwinowski, Joshua B Plotkin
This study develops a mathematical framework to analyze coevolutionary dynamics between antibodies and viruses in chronic infections, identifying parameters and signatures that predict the emergence of broadly neutralizing antibodies.
DOI 10.1371/journal.pgen.1006171