Developmental BiologybioRxiv
Whole organism lineage tracing by combinatorial and cumulative genome editing
Aaron McKenna, Gregory Findlay, James A Gagnon…·Jay Shendure
This study introduces a genome editing method to trace whole organism lineages by accumulating mutations in DNA barcodes, showing that most adult zebrafish cells originate from few embryonic progenitors.
DOI 10.1126/science.aaf7907