Author

Jan Gregor Botthof

Wellcome/MRC Cambridge Stem Cell Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetics· 1

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Approach:experimental assay· 1 Organism:zebrafish· 1

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Ana CvejiciD· 1 shared Ewa Bielczyk-MaczyńskaiD· 1 shared Lauren Ferreira· 1 shared

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GeneticsProceedings of the National Academy of SciencesPeer-reviewedMay 16, 2017

Loss of the homologous recombination gene rad51 leads to Fanconi anemia-like symptoms in zebrafish

Jan Gregor Botthof, Ewa Bielczyk-Maczyńska, Lauren Ferreira, Ana Cvejic

This paper establishes a zebrafish rad51 loss-of-function model that recapitulates Fanconi anemia symptoms, showing hematopoietic defects and tumor predisposition upon p53 co-mutation.

35 citations

zebrafishexperimental assay

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