Author

Janelle Lauer

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Alice Cezanne· 1 shared Andrei LupasiD· 1 shared Christian Johannes GloeckneriD· 1 shared Francesco RaimondiiD· 1 shared Giambattista GuaitoliiD· 1 shared Marc GentzeliD· 1 shared Marino ZerialiD· 1 shared Marius UeffingiD· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperBiophysics

Alice Cezanne

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintFeb 27, 2019

Allosteric structural alterations and auto-regulation of Rab5 GEF activity in Rabex5

Janelle Lauer, Alice Cezanne, Giambattista Guaitoli…·Marino Zerial

This study reevaluates the autoinhibition mechanism of Rabex5 by analyzing structural changes and nucleotide exchange activity, revealing new regulatory roles for Ubiquitin binding domains.

DOI 10.1101/562504

protein structureexperimental assay

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