MicrobiologyACS Synthetic BiologyPeer-reviewed
The biosynthesis of FAD nucleotide analogues in Escherichia coli alters its sensitivity to aminoglycoside antibiotics
Ateek Shah, Shreya Mahato, Prathith Bhargav…·Amrita Brajagopal Hazra
This study shows that engineering FAD biosynthesis in E. coli to produce nucleotide analogues increases tolerance to aminoglycoside antibiotics by altering metabolic pathways.
DOI 10.1021/acssynbio.6c00495