BiophysicsbioRxivPreprint
Single-vesicle tracking of α-synuclein oligomers reveals pore formation by a three-stage model modulated by charge, curvature, lipids and ligands
Bo Volf Brøchner, Xialin Zhang, Janni Nielsen…·Mette Galsgaard Malle
This study uses single-vesicle tracking to show α-synuclein oligomers form pores through a three-stage process influenced by membrane curvature, charge, lipids, and ligands.
DOI 10.1101/2025.04.10.648112