BioengineeringACS Infectious DiseasesPeer-reviewed
Potency of CRISPR-Cas Antifungals Is Enhanced by Co-targeting DNA Repair and Growth Regulatory Machinery at the Genetic Level
Brian J. Mendoza, Xianliang Zheng, Jared C. Clements…·Cong T. Trinh
This paper demonstrates that co-targeting essential and DNA repair genes enhances CRISPR-Cas antifungal efficacy in yeast, outperforming single-target approaches.
11 citations