NeurosciencebioRxivPreprint
The E3 ubiquitin ligase RNF216 contains a linear ubiquitin chain-determining-like domain that functions to regulate dendritic arborization and dendritic spine type in hippocampal neurons
Jayashree Kadirvelu, Savannah E. Jacobs, Ruochuan Liu…·Angela M. Mabb
This study identifies a domain in RNF216 that regulates dendritic arborization and spine morphology through ubiquitin chain assembly, independent of its catalytic activity.
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