Developmental BiologybioRxivPreprint
PDX1 directs a core developmentally and evolutionarily conserved gene program in the pancreatic islet
Xiaodun Yang, Jeffrey C. Raum, Junil Kim…·Diana E. Stanescu
The paper identifies a core set of developmentally and evolutionarily conserved PDX1-bound genes in mouse and human pancreas development, showing stable PDX1 binding across ages with context-dependent regulatory roles.